Marcin Marzejon, PhD

Marcin Marzejon is an optical engineer and researcher specializing in optics and biomedical imaging. He earned his PhD in Electronics summa cum laude from Gdańsk University of Technology, for his contributions to research on the phenomenon of two-photon vision. Currently, he is a Specialist at the Institute of Physical Chemistry PAS, where he develops cutting-edge interferometric near-infrared spectroscopy techniques for noninvasive bioimaging.

Dr. Marzejon has co-authored 9 peer-reviewed scientific papers, 16 conference proceedings, and holds two patents. He has participated in multiple international collaborations, including study visits at Johns Hopkins University and the Centre for Translational Vision Research at the University of California, Irvine. His expertise encompasses fiber optic sensors, Raman spectroscopy, two-photon vision and imaging, and quantitative phase imaging. With a passion for applying optical technologies to solve real-world challenges, Dr. Marzejon also brings experience in software development, data analysis, and system prototyping, leveraging programming tools such as Python, MATLAB, and LabVIEW.

JCR papers:

P. Zdańkowski, J. Winnik, M. Rogalski, M.J. Marzejon, E. Wdowiak, W. Dutka, M. Trusiak, Polarization gratings aided common-path Hilbert holotomography for high-throughput lipid droplets content assay, under review.
M.J. Marzejon, M. Rogalski, M. Trusiak, Affine transform-based twin-image suppression for in-line Lensless Digital Holographic Microscopy, in „Roadmap on Computational Methods in Optical Imaging and Holography [Invited]” by J. Rosen et al., Applied Physics B – Lasers and Optics, in press.
M.J. Marzejon, Ł. Kornaszewski, M. Wojtkowski, K. Komar, Laser pulse train parameters determine the brightness of a two-photon stimulus, Biomedical Optics Express 14(6) 2857-2872 (2023).
D. Stachowiak, M. Marzejon, J. Bogusławski, Z. Łaszczych, K. Komar, M. Wojtkowski, G. Soboń, Femtosecond Er-doped fiber laser source tunable from 872 to 1075 nm for two-photon vision studies in humans, Biomedical Optics Express 13(4), 1899-1011 (2022).
J. Boguslawski, G. Palczewska, S. Tomczewski, J. Milkiewicz, P. Kasprzycki, D. Stachowiak, K. Komar, M.J. Marzejon, B.L. Sikorski, A. Hudzikowski, A. Głuszek, Z. Łaszczych, K. Karnowski, G. Soboń, K. Palczewski, M. Wojtkowski, In vivo imaging of the human eye using a 2-photon-excited fluorescence scanning laser ophthalmoscope, Journal of Clinical Investigation 132(2), e154218 (2022).
K. Karpienko, M.J. Marzejon, A. Mazikowski, J. Pluciński, Quasi-Distributed Network of Low-Coherent Fiber-Optic Fabry-Pérot Sensors with Cavity Length-Based Addressing, Metrology and Measurement Systems 28(2), 289-305 (2021).
M.J. Marzejon, Ł. Kornaszewski, J. Bogusławski, P. Ciąćka, M. Martynow, G. Palczewska, S. Maćkowski, K. Palczewski, M. Wojtkowski, K. Komar, Two-photon microperimetry with picosecond pulses, Biomedical Optics Express 12(1), pp. 462-479 (2021).
M. Marzejon, K. Karpienko, A. Mazikowski, M. Jędrzejewska-Szczerska, Fibre-optic sensor for simultaneous measurement of thickness and refractive index of liquid layers, Metrology and Measurement Systems 26(3), pp. 561-568 (2019).
M. Marzejon, M. Kosowska, D. Majchrowicz, B. Bułło‐Piontecka, M. Wąsowicz, M. Jędrzejewska‐Szczerska, Label‐free optical detection of cyclosporine in biological fluids, Journal of Biophotonics 12(4), pp. e201800273 (2019).
M.J. Marzejon, M. Jędrzejewska-Szczerska, The influence of small amount of substances present in tissue on immunosuppressive drug optical spectrum, Photonics Letters of Poland 10(3), pp. 79-81 (2018).
M. Marzejon, M. Kosowska, D. Majchrowicz, B. Bułło-Piontecka, M. Wąsowicz, M. Jędrzejewska-Szczerska, Optical-Spectrometry-Based Method for Immunosuppressant Medicine Level Detection in Aqueous Solutions, Sensors 18(7), pp. 2001 (2018).

Other papers:

R.F. Aguas, M. Dabrowski, B. Pan, M. Marzejon, A. Kotulska, M.D. Wojtkowski, A. Browne, Refining a Human Two-Photon Imaging System, Investigative Ophthalmology & Visual Science June 2024, Vol.65(7):3424 (2024).
K. Komar, J. Solarz-Niesluchowski, M. Marzejon, J. Pniewski, M. Wojtkowski, Comparison of repeatability of visual thresholds determination for one- and two-photon vision mechanisms, Investigative Ophthalmology & Visual Science June 2023, Vol.64(8):1512 (2023).
O. Kaczkos, A. Zielinska, M. Marzejon, J. Pniewski, M. Wojtkowski, K. Komar, Exploring the contrast sensitivity function for two-photon vision, Investigative Ophthalmology & Visual Science June 2023, Vol.64(8):1495 (2023).
O. Kaczkoś, A. Zielińska, M.J. Marzejon, J. Solarz-Niesłuchowski, J. Pniewski, and K. Komar, Methods of determining the contrast sensitivity function for two-photon vision, Proc. SPIE 12502, 22nd Polish-Slovak-Czech Optical Conference on Wave and Quantum Aspects of Contemporary Optics, 1250215 (2022).
J. Bogusławski, G. Palczewska, M. Dąbrowski, S. Tomczewski, J. Milkiewicz, D. Stachowiak, K. Komar, M. Marzejon, B.L. Sikorski, A. Hudzikowski, A. Głuszek, Z. Łaszczych, G. Soboń, K. Palczewski, M. Wojtkowski, Two-photon excited fluorescence scanning laser ophthalmoscope for in vivo imaging of the human eye, in Biophotonics Congress: Biomedical Optics 2022 (Translational, Microscopy, OCT, OTS, BRAIN), Technical Digest Series (Optica Publishing Group, 2022), paper TTu2B.4 (2022).
A. Zielinska, O. Kaczkos, M. Marzejon, J. Solarz-Niesluchowski, M. Szkulmowski, K. Komar, Contrast Sensitivity Function of Two-Photon Vision, Investigative Ophthalmology & Visual Science June 2022, Vol.63, 2234 – F0442 (2022).
M. Marzejon, A. Zielinska, D. Stachowiak, G. Sobon, M. Wojtkowski, K. Komar, Towards spectral sensitivity curve for two-photon vision mechanism, Investigative Ophthalmology & Visual Science June 2022, Vol.63, 2232 – F0440 (2022).
M.J. Marzejon, Ł. Kornaszewski, J. Bogusławski, M. Wojtkowski, and K. Komar, Swept-sources for OCT are perceived due to two-photon vision, in European Conferences on Biomedical Optics 2021 (ECBO), OSA Technical Digest (Optical Society of America, 2021), paper ETu4A.1.
K. Komar, M.J. Marzejon, A. Matuszak, B. Sikorski, M. Wojtkowski, The effect of cataract on two-photon visual thresholds, Investigative Ophthalmology & Visual Science 62(8), 2009 (2021).
K. Komar, M. Marzejon, A. Matuszak, B. Sikorski, M. Wojtkowski, Two-photon visual sensitivity of cataract patients, in Biophotonics Congress 2021, C. Boudoux, K. Maitland, C. Hendon, M. Wojtkowski, K. Quinn, M. Schanne-Klein, N. Durr, D. Elson, F. Cichos, L. Oddershede, V. Emiliani, O. Maragò, S. Nic Chormaic, N. Pégard, S. Gibbs, S. Vinogradov, M. Niedre, K. Samkoe, A. Devor, D. Peterka, P. Blinder, and E. Buckley, eds., OSA Technical Digest (Optical Society of America, 2021), paper DF2A.4.
M. Marzejon, Ł. Kornaszewski, M. Wojtkowski, K. Komar, Effects of laser pulse duration in two-photon vision threshold measurements, Proc. SPIE 11623, Ophthalmic Technologies XXXI, 116231N (5 March 2021).
M. Martynow, A. Zielińska, M. Marzejon, M. Wojtkowski, K. Komar, Pupil detection supported by Haar feature based cascade classifier for two-photon vision examinations, 11th International Symposium on Image and Signal Processing and Analysis (ISPA), pp. 54-59 (2019).
K. Komar, A. Zielinska, D. Ruminski, M. Marzejon, P. Ciacka, Ł. Kornaszewski, S. Manzanera, P. Artal, M. Wojtkowski, The limits of perception of light by two-photon vision, Investigative Ophthalmology & Visual Science 60(9), pp. 3907-3907 (2019).
M. Marzejon, K. Komar, Ł. Kornaszewski, M. Wojtkowski, Solid state versus fiber picosecond infrared lasers applied to two-photon vision tests, Proc. SPIE 11079, Medical Laser Applications and Laser-Tissue Interactions IX, 110791L (22 July 2019).
M.S. Wróbel, K. Karpienko, M. Marzejon, F. Sadura, S. Siddhanta, I. Barman, J. Smulko, Influence of silver-core gold-shell nanoparticle parameters on the variation of surface-enhanced Raman spectra, Proc. SPIE 11075, Novel Biophotonics Techniques and Applications V, 110751S (22 July 2019).
K. Karpienko, M. Marzejon, J. Pluciński, Fiber optic displacement sensor with signal analysis in spectral domain, Proc. SPIE 10034, 11th Conference on Integrated Optics: Sensors, Sensing Structures, and Methods, 100340K (2 September 2016).

Research groups

The research in our group can be seen as a perfect interplay between physics, biology and chemistry. We are focusing on developing imaging techniques and using them in many biological and chemical systems.

Projects

15.06.2023

Two-Photon Excited-Fluorescence Scanning Laser Ophthalmoscope (TPEF-SLO)

The ability to noninvasively access metabolic processes during the visual cycle is crucial for developing therapies against retinal degenerative diseases. We have developed a protocol for obtaining in vivo two-photon excited fluorescence images of the fundus in the human eye. The visual cycle is a series of chemical transformations during which various fluorescent intermediates are […]

Research groups

Physical Optics and Biophotonics

Projects

Two-Photon Excited-Fluorescence Scanning Laser Ophthalmoscope (TPEF-SLO)