Publications, Patents, Intellectual Property

Adaptive optics-free cone classification using optoretinography based on spatio-temporal optical coherence tomography

Journal of Biomedical Optics

Fast robot-to-iOCT calibration using conical geometry and 2D cross-scan OCT

Scientific Reports

Reducing spatial coherence via dynamic scattering media enables aberration and speckle suppression in optical imaging

Journal of Computational Neuroscience

Intrinsic chaos control in cortical circuits: A minimal E-I-M rate model for primary visual cortex.

Scientific Reports

Hybrid interferometric near infrared spectroscopy (hybrid iNIRS) enables time-of-flight–resolved non-invasive blood flow monitoring in humans in vivo

Frontiers in Computational Neuroscience

NMDA receptor kinetics drive distinct routes to chaotic firing in pyramidal neurons

PLOS ONE

Magnesium neuroprotection in retinal ganglion cells: A computational study of frequency-dependent therapeutic windows and intervention timing

Handbook of Visual Optics, Volume Two

„Two-photon vision” chapter in “Handbook of Visual Optics, Volume Two”

Journal of Biomedical Optics

Spatio-temporal optical coherence imaging and tomography for in vivo applications

Optics Letters

Effect of laser-beam diameter on the visibility of two-photon stimuli

Diabetology

Old Target with New Vision: In Search of New Therapeutics for Diabetic Retinopathy by Selective Modulation of Aldose Reductase

Biomedical Optics Express

Single-shot, depth-encoded multiplexed OCT for multi-spot tracking of induced transient corneal dynamics

Frontiers in Computational Neuroscience

Population-level neural rejuvenation dynamics in addiction: a computational framework for understanding developmental plasticity reactivation

Biocybernetics and Biomedical Engineering

Computational aberration correction enables full-thickness retinal imaging with adaptive optics optical coherence tomography

Translational Vision Science & Technology

Visual Function Loss Through Opacified Media: Comparison Between Single- and Two-Photon Vision

Journal of Optics

Roadmap on Advances in Visual and Physiological Optics

Biocybernetics and Biomedical Engineering

Interferometric speckle contrast optical spectroscopy (iSCOS) in continuous-wave parallel interferometric near-infrared spectroscopy (CW-πNIRS)

TechRxiv

Adaptation of pre-trained single stage detectors for rapid tool pose estimation in OCT-assisted eye surgery

Science Translational Medicine

Retinal polyunsaturated fatty acid supplementation reverses aging-related vision decline in mice

Technical Digest Series

A hybrid time-of-flight-resolved parallel interferometric near-infrared spectroscopy (parallel iNIRS) with a fast two-dimensional and a single-channel iNIRS

Investigative Ophthalmology & Visual Science

Spectral Phasor Approach in Human TPEF-SLO

Biomaterials

Modeling breast cancer dynamics through modulable small Vessel Environment Bioreactor (sVEB)

Investigative Ophthalmology & Visual Science

Comparison of Physiological Brain Responses Evoked byVisual and Electrical Stimulation

NAR Genomics and Bioinformatics

Ocelli: an open-source tool for the analysis and visualization of developmental multimodal single-cell data

Applied Sciences

Dynamic Corneal Response for Different Air-Puff Stimuli in Ex Vivo Animal Model Measured with SS-OCT System with Two Sample Arms

Proceedings of the National Academy of Sciences

Photopic flicker optoretinography captures the light-driven length modulation of photoreceptors during phototransduction

Open Biology

CryoEM structure and small-angle X-ray scattering analyses of porcine retinol-binding protein 3

Biocybernetics and Biomedical Engineering

Imaging of retinal ganglion cells and photoreceptors using Spatio-Temporal Optical Coherence Tomography (STOC-T) without hardware-based adaptive optics

Nature Biomedical Engineering

Safer and efficient base editing and prime editing via ribonucleoproteins delivered through optimized lipid-nanoparticle formulations

STAR Protocols

In vivo volumetric analysis of retinal vascular hemodynamics in mice with spatio-temporal optical coherence tomography

Biomedical Optics Express

Method for the determination of the luminance of two-photon vision stimuli

Nature Communications

A combination treatment based on drug repurposing demonstrates mutation-agnostic efficacy in pre-clinical retinopathy models

Biomedical Optics Express

Time-domain diffuse correlation spectroscopy at large source detector separation for cerebral blood flow recovery

Investigative Ophthalmology & Visual Science

Refining a Human Two-Photon Imaging System

The Journal of Biological Chemistry

Conditional deletion of miR-204 and miR-211 in murine retinal pigment epithelium results in retinal degeneration

IEEE Sensors Journal

Optical coherence tomography imaging by a fully integrated MOEMS endomicroscopy probe with Mirau micro-interferometer and two axis electrothermal micro-scanner using Lissajous trajectory scanning

Optics Letters

Chirped flicker optoretinography for in vivo characterization of human photoreceptors’ frequency response to light

The Journal of Biological Chemistry

Restoring retinal polyunsaturated fatty acid balance and retina function by targeting ceramide in AdipoR1-deficient mice

Vision Research

Two-photon vision – Seeing colors in infrared

Multiwavelength laser doppler holography (MLDH) in spatiotemporal optical coherence tomography (STOC-T)

American Journal of Physiology-Lung Cellular and Molecular Physiology

Quantification of smooth muscle in human airways by polarization-sensitive optical coherence tomography requires correction for perichondrium

Optica

Large reconfigurable quantum circuits with SPAD arrays and multimode fibers

Biocybernetics and Biomedical Engineering

Imaging the retinal and choroidal vasculature using Spatio-Temporal Optical Coherence Tomography (STOC-T)

Frontiers in Medicine

Two-photon excitation fluorescence in ophthalmology: safety and improved imaging for functional diagnostics.

Proceedings of the National Academy of Sciences

Distinct mouse models of Stargardt disease display differences in pharmacological targeting of ceramides and inflammatory responses,

Biomedical Optics Express

Long-range frequency-domain optical delay line based on a spinning tilted mirror for low-cost ocular biometry

bioRxiv

Ocelli: a new comprehensive method for multimodal single-cell data analysis

SPIE Proceedings

Optimization-free method for multiple spectrometers alignment in polarization-sensitive optical coherence tomography

Nature Communications

spinDrop: a droplet microfluidic platform to maximise single-cell sequencing information content

Biomedical Optics Express

Optical beam scanner with reconfigurable non-mechanical control of beam position, angle, and focus for low-cost whole-eye OCT imaging

Investigative Ophthalmology & Visual Science

Comparison of repeatability of visual thresholds determination for one-and two-photon vision mechanisms

Biomedical Optics Express

Laser pulse train parameters determine the brightness of a two-photon stimulus

Proceedings of the National Academy of Sciences

Stress resilience-enhancing drugs preserve tissue structure and function in degenerating retina via phosphodiesterase inhibition

Technical Digest Series

Flicker optoretinography (f-ORG) with chirped frequency stimulus for retinal tissue characterisation

Spatio-temporal optical coherence tomography (STOC-T) for high-resolution imaging of the human and mouse retina in vivo

Technical Digest Series

A low-cost, non-mechanical optical beam scanner: experimental proof-of-concept for whole-eye OCT imaging

Technical Digest Series

Clinical prototype of multi-spot air-puff OCT for assessment of corneal biomechanical asymmetry

Journal of Clinical Investigation

In vivo imaging of the human retina using a two-photon excited fluorescence ophthalmoscope

Improved tool tracking algorithm for eye surgery based on combined color space masks

SPIE Proceedings

Spatio-temporal optical coherence tomography (STOC-T) focal plane adjustment in the mouse retina aided by a fundus camera

SPIE Proceedings

Frequency characterization of human photoreceptors’ response to light with the use of chirped flicker stimulus optoretinography

SPIE Proceedings

High-speed, in vivo, volumetric imaging of mouse retinal tissue with spatio-temporal optical coherence tomography (STOC-T)

Advanced Materials Technologies

Microfluidic 3D Printing of Emulsion Ink for Engineering Porous Functionally Graded Materials

SPIE Proceedings

Intraoperative ophthalmic OCT system tracking surgical tools at 200 Hz

SPIE Proceedings

Low-resource and cost-effective camera-based optical palpation for breast cancer detection and burn scar assessment

International Journal of Molecular Sciences

Towards a New Biomarker for Diabetic Retinopathy: Exploring RBP3 Structure and Retinoids Binding for Functional Imaging of Eyes In Vivo

Progress in Retinal and Eye Research

From mouse to human: Accessing the biochemistry of vision in vivo by two-photon excitation.

Biomedical Optics Express

Estimation of the full shape of the crystalline lens in-vivo from OCT images using eigenlenses

22nd Polish-Slovak-Czech Optical Conference on Wave and Quantum Aspects of Contemporary Optics

Methods of determining the contrast sensitivity function for two-photon vision

Aging Cell

Stress induced aging in mouse eye.

Membranes

The Structural Changes in the Membranes of Staphylococcus aureus Caused by Hydrolysable Tannins Witness Their Antibacterial Activity

Scientific Reports

Co-axial acoustic-based optical coherence vibrometry probe for the quantification of resonance frequency modes in ocular tissue

Technical Digest Series

Functional and Structural Imaging of Retinal Tissue with Spatio-Temporal Optical Coherence Tomography (STOC-T)

Biomedical Optics Express

Continuous-wave parallel interferometric near-infrared spectroscopy (CW πNIRS) with a fast two-dimensional camera

IEEE Photonics Journal

Superior Imaging Performance of All-Fiber, Two-Focusing-Element Microendoscopes

eNeuro

Visual System Hyperexcitability and Compromised V1 Receptive Field Properties in Early-Stage Retinitis Pigmentosa in Mice.

Investigative Ophthalmology & Visual Science

Contrast Sensitivity Function of Two-Photon Vision

Investigative Ophthalmology & Visual Science

Towards spectral sensitivity curve for two-photon vision mechanism

Investigative Ophthalmology & Visual Science

Two-photon excited scanning laser ophthalmoscope enables fundus imaging in healthy volunteers

iScience

Spatio-Temporal Optical Coherence Tomography provides full thickness imaging of the chorioretinal complex

Lab on a Chip

You will know by its tail: a method for quantification ofheterogeneity of bacterial populations using single-cell MICprofiling

Physica B: Condensed Matter

Propagation length enhancement of surface plasmon polaritons in ultrafine Au nanodisk array, the role of kinky breather and periodic lump

Technical Digest Series

Design of a low-cost, versatile, whole-eye scanner for optical coherence tomography

Technical Digest Series

Hysteresis in vibrational resonance modes of model corneas measured with Optical Coherence Tomography Vibrography utilizing a co-axial acoustic stimulation technique and pre-compensation

Technical Digest Series

In vivo frequency characterization of human photoreceptors response to a flicker stimulus with optoretinography

Technical Digest Series

Simultaneous multi-spot OCT measurements of air induced corneal deformations

Nature Communications

In vivo base editing rescues cone photoreceptors in a mouse model of early-onset inherited retinal degeneration.

Biomedical Optics Express

Light-adapted flicker optoretinograms captured with a spatio-temporal optical coherence-tomography (STOC-T) system

Pathogens

Both Neisseria gonorrhoeae and Neisseria sicca Induce Cytokine Secretion by Infected Human Cells, but Only Neisseria gonorrhoeae Upregulates the Expression of Long Non-Coding RNAs

Diagnostics

Two-Photon Vision in Age-Related Macular Degeneration: ATranslational Study

Biomedical Optics Express

Femtosecond Er-doped fiber laser source tunable from 872 to 1075 nm for two-photon vision studies in humans

Scientific Reports

Infrared- and white-light retinal sensitivity in glaucomatous neuropathy

Optics Letters

Multimode fiber as a tool to reduce crosstalk in Fourier-domain full-field optical coherence tomography

Acta Neurobiologiae Experimentalis

Optical coherence tomography reveals heterogeneity of the brain tissue and vasculature in the ischemic region after photothrombotic stroke in mice

SPIE BiOS

A novel co-axial and acoustic pre-compensation approach for tissue excitation in optical coherence tomography vibrography

SPIE BiOS

Air puff-coupled multi-spot OCT for assessment of asymmetries in corneal biomechanics

SPIE Proceedings

Corneal biomechanical parameters of keratoconus patients from cross-meridian air-puff deformation optical coherence tomography and finite element modeling

SPIE Proceedings

Towards spatially mapped frequency response of human photoreceptor length variation with flicker optoretinography

Journal of Clinical Investigation

In vivo imaging of the human eye using a two-photon excited fluorescence scanning laser ophthalmoscope

JCI Insight

Inhibition of ceramide accumulation in AdipoR1–/– mice increases photoreceptor survival and improves vision

Investigative Ophthalmology & Visual Science

Pupillary Light Reflex induced by two-photon vision

ACS omega

Characterization of Cyclophilin from Thaumarchaeota Nitrosopumilus maritimus: Implications on the Diversity of Chaperone-like Activity in the Archaeal Domain.

Technical Digest Series

Two-photon excited fluorescence scanning laser ophthalmoscope for in vivo imaging of the human eye

Communications Biology

Traumatic brain injury to primary visual cortex produces long-lasting circuit dysfunction

Biomedical Optics Express

Estimation of scleral mechanical properties from air-puff optical coherence tomography

Investigative Ophthalmology & Visual Science

The effect of cataract on two-photon visual thresholds

Technical Digest Series

Swept-sources for OCT are perceived due to two-photon vision

APL Photonics

Imaging the small with the small: Prospects for photonics in micro-endomicroscopy for minimally invasive cellular-resolution bioimaging

Biomedical Optics Express

Smartphone-based optical palpation: towards elastography of skin for telehealth applications

Investigative Ophthalmology & Visual Science

Improved detection of corneal deformation asymmetries in keratoconus patients using multi-meridian deformation imaging

Optics Letters

Multimode fiber enables control of spatial coherence in Fourier-domain full-field optical coherence tomography for in vivo corneal imaging

SPIE Proceedings

Effects of laser pulse duration in two-photon vision threshold measurements

Biomedical Optics Express

Two-photon microperimetry with picosecond pulses

Analytical Chemistry

High-Throughput Monitoring of Bacterial Cell Density in Nanoliter Droplets: Label-Free Detection of Unmodified Gram-Positive and Gram-Negative Bacteria

XIII Spanish National Meeting on Optics, Sedoptica

Applications of the ImTOPScanner for the investigation of ocular biomechanical parameters

SPIE Proceedings

Optical Coherence Elastography Imaging Probes

Nature Biomedical Engineering

Restoration of visual function in adult mice with an inherited retinal disease via adenine base editing

Industrialization Potential of Optics in Biomedicine i-POB

High-frame rate multi-meridian corneal imaging of air-puff induced deformation for improved detection of keratoconus

Journal of Biomedical Optics

Influence of tissue fixation on depth-resolved birefringence of oral cavity tissue samples

Proceedings of the National Academy of Sciences

Noninvasive two-photon optical biopsy of retinal fluorophores

Biomedical Optics Express

Multi-meridian corneal imaging of air-puff induced deformation for improved detection of biomechanical abnormalities

Biomedical Optics Express

Longitudinal in-vivo OCM imaging of glioblastoma development in the mouse brain

Frontiers in Systems Neuroscience

Cortical Inactivation Does Not Block Response Enhancement in the Superior Colliculus

Biomedical Optics Express

Frequency-doubled femtosecond Er-doped fiber laser for two-photon excited fluorescence imaging

Translational Vision Science & Technology

Keratoconus Detection Based on a Single Scheimpflug Image

Journal of Biophotonics

Jones matrix-based speckle-decorrelation angiography using polarization-sensitive optical coherence tomography

Optics Letters

Computational aberration correction in spatiotemporal optical coherence (STOC) imaging

Biomedical Optics Express

Vectorial birefringence imaging by optical coherence microscopy for assessing fibrillar microstructures in the cornea and limbus

Biomedical Optics Express

Crosstalk-free volumetric in vivo imaging of a human retina with Fourier-domain full-field optical coherence tomography

2019 11th International Symposium on Image and Signal Processing and Analysis (ISPA)

Pupil detection supported by Haar feature based cascade classifier for two-photon vision examinations

Biomedical Optics Express

Two-photon microperimetry: sensitivity of human photoreceptors to infrared light

SPIE Proceedings

Solid state versus fiber picosecond infrared lasers applied to two-photon vision tests

Investigative Ophthalmology & Visual Science

The limits of perception of light by two-photon vision

Photonics Letters of Poland

Impact of diurnal IOP variations on the dynamic corneal hysteresis measured with air-puff swept-source OCT