Physical Optics and Biophotonics
Principal Investigator:
Prof. dr hab. Maciej Wojtkowski
The research in our group can be seen as a synergistic interplay of physics, biology, and chemistry. We are focused on developing imaging techniques and using them in many biological and chemical systems. The uniqueness of our approach is using not only the amplitude of the light but also its phase in order to develop new, world-class imaging systems. Optical Coherence Tomography is a great example of such a method, and we are advancing its capabilities by implementing an innovative method for removal of image distortion ― STOC (Spatio Temporal Optical Coherence manipulation), which has the potential to largely increase the quality of imaging through opaque layers, such as skin.
All projects are aimed to bring to humanity new non-invasive imaging techniques, that will enhance our understanding of nature, increase quality of life, and extend longevity.
POB Address: ICTER Headquarters, Skierniewicka 10A, 01-230 Warsaw
Phone number: +48 607 293 453
Group Leader: mwojtkowski@ichf.edu.pl
Team Coordinator: asalamonczyk@ichf.edu.pl
Principal Investigator
Group Coordinator and Lab Manager
Post-docs
Jakub Bogusławski, PhD
Visiting Researcher
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Dawid Borycki, PhD
Senior Researcher
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Karol Karnowski, PhD
Senior Researcher
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Piotr Kasprzycki PhD
Post-doc
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Kamil Liżewski, PhD
Post-doc
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Sławomir Tomczewski, PhD
Post-doc
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Michał Dąbrowski, PhD
Post-doc
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Katarzyna Komar, PhD
Senior Researcher
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Agata Kotulska, PhD
Post-doc
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Marta Mikuła-Zdańkowska, PhD Eng.
Post-doc
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Publications
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22nd Polish-Slovak-Czech Optical Conference on Wave and Quantum Aspects of Contemporary Optics
Methods of determining the contrast sensitivity function for two-photon vision
10.1117/12.2664174
2022
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Advanced Materials Technologies
Microfluidic 3D Printing of Emulsion Ink for Engineering Porous Functionally Graded Materials
10.1002/admt.202201244
2022
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iScience
Spatio-Temporal Optical Coherence Tomography provides full thickness imaging of the chorioretinal complex
10.1016/j.isci.2022.105513
2022
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Biomedical Optics Express
Continuous-wave parallel interferometric near-infrared spectroscopy (CW πNIRS) with a fast two-dimensional camera
10.1364/BOE.472643
2022
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Lab on a Chip
You will know by its tail: a method for quantification of
heterogeneity of bacterial populations using single-cell MIC
profiling10.1039/D2LC00234E
2022
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IEEE Photonics Journal
Superior Imaging Performance of All-Fiber, Two-Focusing-Element Microendoscopes
10.1109/JPHOT.2022.3203219
2022
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Investigative Ophthalmology & Visual Science
Towards spectral sensitivity curve for two-photon vision mechanism
2022
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Investigative Ophthalmology & Visual Science
Contrast Sensitivity Function of Two-Photon Vision
2022
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Investigative Ophthalmology & Visual Science
Two-photon excited scanning laser ophthalmoscope enables fundus imaging in healthy volunteers
2022
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Diagnostics
Two-Photon Vision in Age-Related Macular Degeneration: A
Translational Study10.3390/diagnostics12030760
2022
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Biomedical Optics Express
Femtosecond Er-doped fiber laser source tunable from 872 to 1075 nm for two-photon vision studies in humans
10.1364/BOE.452609
2022
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Optics Letters
Multimode fiber as a tool to reduce crosstalk in Fourier-domain full-field optical coherence tomography
10.1364/OL.449498
2022
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Scientific Reports
Infrared- and white-light retinal sensitivity in glaucomatous neuropathy
10.1038/s41598-022-05718-6
2022
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Acta Neurobiol Exp
Optical coherence tomography reveals heterogeneity of the brain tissue and vasculature in the ischemic region after photothrombotic stroke in mice
DOI: 10.55782/ane‑2022‑010
2022
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Journal of Clinical Investigation
In vivo imaging of the human eye using a two-photon excited fluorescence scanning laser ophthalmoscope
10.1172/JCI154218
2022
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Investigative Ophthalmology & Visual Science
Pupillary Light Reflex induced by two-photon vision
10.1167/iovs.62.15.23
2021
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Biophotonics Congress: Biomedical Optics 2022 (Translational, Microscopy, OCT, OTS, BRAIN), Technical Digest Series
Two-photon excited fluorescence scanning laser ophthalmoscope for in vivo imaging of the human eye
10.1364/TRANSLATIONAL.2022.TTu2B.4
2021
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nvestigative Ophthalmology & Visual Science
The effect of cataract on two-photon visual thresholds
(none)
2021
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European Conferences on Biomedical Optics 2021 (ECBO), OSA Technical Digest (Optical Society of America, 2021)
Swept-sources for OCT are perceived due to two-photon vision
2021
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APL Photonics
Imaging the small with the small: Prospects for photonics in micro-endomicroscopy for minimally invasive cellular-resolution bioimaging
10.1063/5.0052258
2021
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Optics Letters
Multimode fiber enables control of spatial coherence in Fourier-domain full-field optical coherence tomography for in vivo corneal imaging
10.1364/OL.417178
2021
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Proceedings , Ophthalmic Technologies XXXI;
Effects of laser pulse duration in two-photon vision threshold measurements
https://doi.org/10.1117/12.2582735
2021
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Biomedical Optics Express
Two-photon microperimetry with picosecond pulses
10.1364/BOE.411168
2020
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Analytical Chemistry
High-Throughput Monitoring of Bacterial Cell Density in Nanoliter Droplets: Label-Free Detection of Unmodified Gram-Positive and Gram-Negative Bacteria
10.1021/acs.analchem.0c03408
2020
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Journal of Biomedical Optics
Influence of tissue fixation on depth-resolved birefringence of oral cavity tissue samples
10.1117/1.JBO.25.9.096003
2020
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Proceedings of the National Academy of Sciences
Noninvasive two-photon optical biopsy of retinal fluorophores
10.1073/pnas.2007527117
2020
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Biomedical Optics Express
Longitudinal in-vivo OCM imaging of glioblastoma development in the mouse brain
10.1364/BOE.400723
2020
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Biomedical Optics Express
Frequency-doubled femtosecond Er-doped fiber laser for two-photon excited fluorescence imaging
10.1364/BOE.396878
2020
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Translational Vision Science & Technology
Keratoconus Detection Based on a Single Scheimpflug Image
10.1167/tvst.9.7.36
2020
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Journal of Biophotonics
Jones matrix-based speckle-decorrelation angiography using polarization-sensitive optical coherence tomography
10.1002/jbio.202000007
2020
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Optics Letters
Computational aberration correction in spatiotemporal optical coherence (STOC) imaging
10.1364/OL.384796
2020
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Biomedical Optics Express
Vectorial birefringence imaging by optical coherence microscopy for assessing fibrillar microstructures in the cornea and limbus
10.1364/BOE.382755
2020
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Biomedical Optics Express
Crosstalk-free volumetric in vivo imaging of a human retina with Fourier-domain full-field optical coherence tomography
10.1364/BOE.10.006390
2019
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2019 11th International Symposium on Image and Signal Processing and Analysis (ISPA)
Pupil detection supported by Haar feature based cascade classifier for two-photon vision examinations
10.1109/ISPA.2019.8868706
2019
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Biomedical Optics Express
Two-photon microperimetry: sensitivity of human photoreceptors to infrared light
10.1364/BOE.10.004551
2019
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Proc. SPIE 11079, Medical Laser Applications and Laser-Tissue Interactions IX
Solid state versus fiber picosecond infrared lasers applied to two-photon vision tests
10.1117/12.2527118
2019
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Investigative Ophthalmology & Visual Science
The limits of perception of light by two-photon vision
(none)
2019
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Photonics Letters of Poland
Impact of diurnal IOP variations on the dynamic corneal hysteresis measured with air-puff swept-source OCT
10.4302/plp.v10i3.848
2018
