Physical Optics and Biophotonics
The research in our group can be seen as a synergistic interplay of physics, biology, and chemistry. We are focused on developing imaging techniques and using them in many biological and chemical systems. The uniqueness of our approach is using not only the amplitude of the light but also its phase in order to develop new, world-class imaging systems. Optical Coherence Tomography is a great example of such a method, and we are advancing its capabilities by implementing an innovative method for removal of image distortion ― STOC (Spatio Temporal Optical Coherence manipulation), which has the potential to largely increase the quality of imaging through opaque layers, such as skin.
All projects are aimed to bring to humanity new non-invasive imaging techniques, that will enhance our understanding of nature, increase quality of life, and extend longevity.
POB Address: ICTER Headquarters, Skierniewicka 10A, 01-230 Warsaw
Phone number: +48 607 293 453
Group Leader: mwojtkowski@ichf.edu.pl
Team Coordinator: asalamonczyk@ichf.edu.pl
Principal Investigator
Group Coordinator and Lab Manager
Senior researchers
Post-docs
PhD Students
Past members
Egidijus Auksorius, PhD
Jakub Bogusławski, PhD
Piotr Ciąćka, PhD
Onur Çetinkaya, BEng
Marcin Marzejon, PhD
Rafał Pietruch
Mounika Rapolu, PhD
Saeed Samaei
Publications
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Biomedical Optics Express
Time-domain diffuse correlation spectroscopy at large source detector separation for cerebral blood flow recovery
10.1364/BOE.523514 -
Biocybernetics and Biomedical Engineering
Multiwavelength laser doppler holography (MLDH) in spatiotemporal optical coherence tomography (STOC-T)
10.1016/j.bbe.2024.03.002 -
Optica
Large reconfigurable quantum circuits with SPAD arrays and multimode fibers
10.1364/OPTICA.506943 -
Biocybernetics and Biomedical Engineering
Imaging the retinal and choroidal vasculature using Spatio-Temporal Optical Coherence Tomography (STOC-T)
10.1016/j.bbe.2023.12.002 -
SPIE Proceedings
Optimization-free method for multiple spectrometers alignment in polarization-sensitive optical coherence tomography
10.1117/12.2670617 -
Biomedical Optics Express
Laser pulse train parameters determine the brightness of a two-photon stimulus
10.1364/BOE.489890 -
STAR Protocols
In vivo imaging of the human retina using a two-photon excited fluorescence ophthalmoscope
10.1016/j.xpro.2023.102225 -
Progress in Retinal and Eye Research
From mouse to human: Accessing the biochemistry of vision in vivo by two-photon excitation.
10.1016/j.preteyeres.2023.101170 -
22nd Polish-Slovak-Czech Optical Conference on Wave and Quantum Aspects of Contemporary Optics
Methods of determining the contrast sensitivity function for two-photon vision
10.1117/12.2664174 -
Advanced Materials Technologies
Microfluidic 3D Printing of Emulsion Ink for Engineering Porous Functionally Graded Materials
10.1002/admt.202201244 -
iScience
Spatio-Temporal Optical Coherence Tomography provides full thickness imaging of the chorioretinal complex
10.1016/j.isci.2022.105513 -
Biomedical Optics Express
Continuous-wave parallel interferometric near-infrared spectroscopy (CW πNIRS) with a fast two-dimensional camera
10.1364/BOE.472643 -
Lab on a Chip
You will know by its tail: a method for quantification of
heterogeneity of bacterial populations using single-cell MIC
profiling10.1039/D2LC00234E -
IEEE Photonics Journal
Superior Imaging Performance of All-Fiber, Two-Focusing-Element Microendoscopes
10.1109/JPHOT.2022.3203219 -
Investigative Ophthalmology & Visual Science
Towards spectral sensitivity curve for two-photon vision mechanism
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Investigative Ophthalmology & Visual Science
Contrast Sensitivity Function of Two-Photon Vision
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Investigative Ophthalmology & Visual Science
Two-photon excited scanning laser ophthalmoscope enables fundus imaging in healthy volunteers
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Diagnostics
Two-Photon Vision in Age-Related Macular Degeneration: A
Translational Study10.3390/diagnostics12030760 -
Biomedical Optics Express
Femtosecond Er-doped fiber laser source tunable from 872 to 1075 nm for two-photon vision studies in humans
10.1364/BOE.452609 -
Optics Letters
Multimode fiber as a tool to reduce crosstalk in Fourier-domain full-field optical coherence tomography
10.1364/OL.449498 -
Scientific Reports
Infrared- and white-light retinal sensitivity in glaucomatous neuropathy
10.1038/s41598-022-05718-6 -
Acta Neurobiol Exp
Optical coherence tomography reveals heterogeneity of the brain tissue and vasculature in the ischemic region after photothrombotic stroke in mice
DOI: 10.55782/ane‑2022‑010 -
Journal of Clinical Investigation
In vivo imaging of the human eye using a two-photon excited fluorescence scanning laser ophthalmoscope
10.1172/JCI154218 -
Investigative Ophthalmology & Visual Science
Pupillary Light Reflex induced by two-photon vision
10.1167/iovs.62.15.23 -
Biophotonics Congress: Biomedical Optics 2022 (Translational, Microscopy, OCT, OTS, BRAIN), Technical Digest Series
Two-photon excited fluorescence scanning laser ophthalmoscope for in vivo imaging of the human eye
10.1364/TRANSLATIONAL.2022.TTu2B.4 -
nvestigative Ophthalmology & Visual Science
The effect of cataract on two-photon visual thresholds
(none) -
European Conferences on Biomedical Optics 2021 (ECBO), OSA Technical Digest (Optical Society of America, 2021)
Swept-sources for OCT are perceived due to two-photon vision
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APL Photonics
Imaging the small with the small: Prospects for photonics in micro-endomicroscopy for minimally invasive cellular-resolution bioimaging
10.1063/5.0052258 -
Optics Letters
Multimode fiber enables control of spatial coherence in Fourier-domain full-field optical coherence tomography for in vivo corneal imaging
10.1364/OL.417178 -
Proceedings , Ophthalmic Technologies XXXI;
Effects of laser pulse duration in two-photon vision threshold measurements
https://doi.org/10.1117/12.2582735 -
Biomedical Optics Express
Two-photon microperimetry with picosecond pulses
10.1364/BOE.411168 -
Analytical Chemistry
High-Throughput Monitoring of Bacterial Cell Density in Nanoliter Droplets: Label-Free Detection of Unmodified Gram-Positive and Gram-Negative Bacteria
10.1021/acs.analchem.0c03408 -
Journal of Biomedical Optics
Influence of tissue fixation on depth-resolved birefringence of oral cavity tissue samples
10.1117/1.JBO.25.9.096003 -
Proceedings of the National Academy of Sciences
Noninvasive two-photon optical biopsy of retinal fluorophores
10.1073/pnas.2007527117 -
Biomedical Optics Express
Longitudinal in-vivo OCM imaging of glioblastoma development in the mouse brain
10.1364/BOE.400723 -
Biomedical Optics Express
Frequency-doubled femtosecond Er-doped fiber laser for two-photon excited fluorescence imaging
10.1364/BOE.396878 -
Translational Vision Science & Technology
Keratoconus Detection Based on a Single Scheimpflug Image
10.1167/tvst.9.7.36 -
Journal of Biophotonics
Jones matrix-based speckle-decorrelation angiography using polarization-sensitive optical coherence tomography
10.1002/jbio.202000007 -
Optics Letters
Computational aberration correction in spatiotemporal optical coherence (STOC) imaging
10.1364/OL.384796 -
Biomedical Optics Express
Vectorial birefringence imaging by optical coherence microscopy for assessing fibrillar microstructures in the cornea and limbus
10.1364/BOE.382755 -
Biomedical Optics Express
Crosstalk-free volumetric in vivo imaging of a human retina with Fourier-domain full-field optical coherence tomography
10.1364/BOE.10.006390 -
2019 11th International Symposium on Image and Signal Processing and Analysis (ISPA)
Pupil detection supported by Haar feature based cascade classifier for two-photon vision examinations
10.1109/ISPA.2019.8868706 -
Biomedical Optics Express
Two-photon microperimetry: sensitivity of human photoreceptors to infrared light
10.1364/BOE.10.004551 -
Proc. SPIE 11079, Medical Laser Applications and Laser-Tissue Interactions IX
Solid state versus fiber picosecond infrared lasers applied to two-photon vision tests
10.1117/12.2527118 -
Investigative Ophthalmology & Visual Science
The limits of perception of light by two-photon vision
(none) -
Photonics Letters of Poland
Impact of diurnal IOP variations on the dynamic corneal hysteresis measured with air-puff swept-source OCT
10.4302/plp.v10i3.848