The seminar discusses a single-cell meta-analysis of SARS-CoV-2 entry genes across tissues and demographics. It focuses on ACE2 and accessory proteases such as TMPRSS2 and CTSL, their cell-type-specific expression, and how age, sex and smoking may influence susceptibility to infection and COVID-19 pathology.
About the speaker
Christoph Muus is affiliated with Harvard University, the School of Engineering and Applied Sciences, and the Broad Institute of MIT and Harvard in Cambridge, USA