16.12.2024 Our collaborative research with ICTER focuses on advancing vision restoration therapies and fundamental investigations of retinal function using animal models. The team has already established a sophisticated Full-field Optical Coherence Tomography (FF-OCT) system specifically designed for mouse model imaging, capable of capturing both structural and functional retinal characteristics with exceptional precision.
To support the critical retinal injection procedures essential for therapeutic interventions, we are developing an advanced 1060 nm swept-source OCT system. This innovative imaging platform will serve multiple crucial functions, primarily providing real-time image guidance for automated eye injections. Beyond its primary injection support role, the system offers additional versatility by functioning as a comprehensive preview and eye alignment mechanism for our Full-field OCT research studies.
The 1060 nm wavelength was carefully selected to optimize imaging penetration and resolution, ensuring clear visualization of delicate retinal structures during complex therapeutic interventions. By integrating precise image guidance directly into the injection process, we aim to enhance the accuracy, safety, and potential effectiveness of emerging vision restoration techniques.
Text: Karol Karnowski, PhD, Acting IDoc Leader
Project team:
Karol Karnowski
Wiktor Kulesza
Jadwiga Milkiewicz
Piotr Nalewajko
Project in collaboration with other ICTER’s POB and OBi groups.
Related funding: IRAP (MAB) FENG by FNP
Reference:
- Piotr Węgrzyn, Wiktor Kulesza, Maciej Wielgo, Sławomir Tomczewski, Anna Galińska, Bartłomiej Bałamut, Katarzyna Kordecka, Onur Cetinkaya, Andrzej Foik, Robert J. Zawadzki, Dawid Borycki, Maciej Wojtkowski, and Andrea Curatolo “In vivo volumetric analysis of retinal vascular hemodynamics in mice with spatio-temporal optical coherence tomography,” Neurophotonics 11(4), 045003 (8 October 2024). https://doi.org/10.1117/1.NPh.11.4.045003
