Computational Genomics Group
Research in our lab focuses on embracing high-throughput single-cell sequencing technologies to understand a cellular heterogeneity of healthy and diseased complex tissues with particular focus on the eye. We encourage highly motivated individuals at all levels of scientific training and background to reach out me regarding opportunities in our lab.
Research Summary
To gain valuable insights into complex biological systems and processes, it is essential to measure features of interest in individual cells. The single-cell transcriptomics and epigenomics allow researchers to uncover rare cell types, reveal the diversity of cell populations, infer the developmental trajectories of cell lineages, and discover their regulatory mechanisms. Recent progress in developing high-throughput single-cell methods allows researchers to study cell types and states of a tremendous number of cells (1 million and beyond).
Contact details:
Phone: +48 609 877 462
Leader: Marcin Tabaka, mtabaka@ichf.edu.pl
Coordinator: Lidia Wolińska-Nizioł, lwolinska-niziol@ichf.edu.pl
Team:
Leader:
Marcin Tabaka
Projects: OPUS 21 2021/41/B/NZ7/03786
Science for the Society NdS-II/SP/0195/2023/01
OPUS 25 2023/49/B/NZ9/01925
MAB II (FENG.02.01IP.05-T005/23)
Post-docs:
Joanna Bem
Project: Weave-Unisono 2023/05/Y/NZ6/00083
Aleksandra Kornacka-Stackonis
Project: Sonata Bis 12 2022/46/E/NZ2/00370
Natalia Ochocka-Lewicka
Project: Sonatina 8 2024/52/C/NZ2/00230
Science for the Society NdS-II/SP/0195/2023/01
Stefania Robakiewicz
Project: MAB II (FENG.02.01IP.05-T005/23)
PhD students:
Maciej Ficek
Project: Sonata Bis 12 2022/46/E/NZ2/00370
Piotr Rutkowski
Project: Preludium 2022/45/N/NZ2/02311
Research specialist:
Kamil Krawczyński
Project: Sonata Bis 12 2022/46/E/NZ2/00370
Bioinformatician:
Damian Panas
Project: MAB II (FENG.02.01IP.05-T005/23)
Technical specialist:
Nataliya Galagan
Project: Science for the Society NdS-II/SP/0195/2023/01
Lidia Wolińska-Nizioł
Project: MAB II (FENG.02.01IP.05-T005/23)
Interns:
Hussein Nasrallah
Eramus+ Intership
Katarzyna Wojtak
Project: Sonatina 8 2024/52/C/NZ2/00230
Katarzyna Michalak
Project: Weave-Unisono 2023/05/Y/NZ6/00083
Principal Investigator
Group Coordinator and Lab Manager
Post-docs
Research Engineers
Students
Publications
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The Journal of Biological Chemistry
Conditional deletion of miR-204 and miR-211 in murine retinal pigment epithelium results in retinal degeneration
10.1016/j.jbc.2024.1073442024
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The Journal of Biological Chemistry
Restoring retinal polyunsaturated fatty acid balance and retina function by targeting ceramide in AdipoR1-deficient mice
DOI: 10.1016/j.jbc.2024.1072912024
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bioRxiv
Ocelli: a new comprehensive method for multimodal single-cell data analysis
10.1101/2023.10.05.5610742023
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Nature Communications
spinDrop: a droplet microfluidic platform to maximise single-cell sequencing information content
10.1038/s41467-023-40322-w2023
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Proceedings of the National Academy of Sciences (PNAS)
Stress resilience-enhancing drugs preserve tissue structure and function in degenerating retina via phosphodiesterase inhibition
DOI: 10.1073/pnas.22210451202023