Joanna Bem, PhD
PhD in Biology degree from the University of Warsaw
Postdoctoral Researcher
epigenetics, transcriptional regulation and cellular differentiation
Description
Postdoctoral fellow at the Computational Genomics Group (CGG) led by Dr. Marcin Tabaka, and coordinated by Dr. Lidia Wolińska-Nizioł. Since July 2024, Joanna is involved in the Weave-UNISONO bilateral research project funded by the NCN (National Science Centre) in cooperation with the SNSF (Swiss National Science Foundation). In a joint project with Prof. Alfred Zippelius and Dr. Karen Dixon (Department of Biomedicine, University of Basel) she will employ multimodal single cell mapping to elucidate the role that immune system plays in cancer.
Joanna graduated from the University of Warsaw, Faculty of Biology in 2010. There, her fascination with epigenetics and development has started. She obtained her PhD degree at the University of Warsaw in 2018, she was involved in a project investigating the role of miRNAs in stem cells’ differentiation. During a post-doc fellowship at the Centre of New Technologies, University of Warsaw she focused specifically on transcriptional regulation, and 3D chromatin structure in terminal neuronal differentiation. Later she joined the International Institute of Molecular Mechanisms and Machines, where she was engaged in research on the transcriptional memory. Dr. Joanna Bem is an author or co-author of 6 original papers, 2 reviews publications and also contributed to 2 patents. During her scientific career she led one scientific project founded by NCN and several intramural-microgrants.
During free time, Joanna enjoys gardening and creating ceramic pottery.
Project: Weave-Unisono 2023/05/Y/NZ6/00083.
Publication list
- Archacka K, Bem J, Brzoska E, Czerwinska AM, Grabowska I, Kasprzycka P, Hoinkis D, Siennicka K, Pojda Z, Bernas P, Binkowski R, Jastrzebska K, Kupiec A, Malesza M, Michalczewska E, Soszynska M, Ilach K, Streminska W, Ciemerych MA. Beneficial Effect of IL-4 and SDF-1 on Myogenic Potential of Mouse and Human Adipose Tissue-Derived Stromal Cells. Cells. 2020 Jun 17;9(6):1479. PMID: 32560483.
- Zimowska M, Archacka K, Brzoska E, Bem J, Czerwinska AM, Grabowska I, Kasprzycka P, Michalczewska E, Stepaniec I, Soszynska M, Ilach K, Streminska W, Ciemerych MA. IL-4 and SDF-1 Increase Adipose Tissue-Derived Stromal Cell Ability to Improve Rat Skeletal Muscle Regeneration. Int J Mol Sci. 2020 May 7;21(9):3302. PMID: 32392778.
- Lipiec MA, Bem J, Koziński K, Chakraborty C, Urban-Ciećko J, Zajkowski T, Dąbrowski M, Szewczyk ŁM, Toval A, Ferran JL, Nagalski A, Wiśniewska MB. TCF7L2 regulates postmitotic differentiation programmes and excitability patterns in the thalamus. 2020 Aug 25;147(16):dev190181. PMID: 32675279.
- Grabowska I, Zimowska M, Maciejewska K, Jablonska Z, Bazga A, Ozieblo M, Streminska W, Bem J, Brzoska E, Ciemerych MA. Adipose Tissue-Derived Stromal Cells in Matrigel Impacts the Regeneration of Severely Damaged Skeletal Muscles. Int J Mol Sci. 2019 Jul 5;20(13):3313. PMID: 31284492.
- Bem J, Brożko N, Chakraborty C, Lipiec MA, Koziński K, Nagalski A, Szewczyk ŁM, Wiśniewska MB. Wnt/β-catenin signaling in brain development and mental disorders: keeping TCF7L2 in mind. FEBS Lett. 2019 Jul;593(13):1654-1674. PMID: 31218672.
- Bem J, Grabowska I, Daniszewski M, Zawada D, Czerwinska AM, Bugajski L, Piwocka K, Fogtman A, Ciemerych MA. Transient MicroRNA Expression Enhances Myogenic Potential of Mouse Embryonic Stem Cells. Stem Cells. 2018 May;36(5):655-670. PMID: 29314416.
- Czerwinska AM, Grabowska I, Archacka K, Bem J, Swierczek B, Helinska A, Streminska W, Fogtman A, Iwanicka-Nowicka R, Koblowska M, Ciemerych MA. Myogenic Differentiation of Mouse Embryonic Stem Cells That Lack a Functional Pax7 Gene. Stem Cells Dev. 2016 Feb 15;25(4):285-300. PMID: 26649785; PMCID: PMC4761802.
- Bem J, Grabowska I. Alchemia epigenetycznej regulacji pluripotencji [The alchemy–epigenetic regulation of pluripotency]. Postepy Biochem. PMID: 24044279.
Research projects
Research groups
We are interested in creating new approaches for comprehensive inference of developmental trajectories and delineation of cell atlases from single-cell data, understanding the role of cell-to-cell signaling and biological pathways in lineage commitment and transitions between cellular states.
