Project title: Parallel interferometric near-infrared spectroscopy for noninvasive monitoring of the cerebral blood flow in humans in vivo.

This project aims to develop a fast optical system for noninvasive continuous cerebral blood flow monitoring in humans in vivo. To achieve this goal, we aim to parallelize the iNIRS system. The collected optical signals will be recorded using a two-dimensional camera operating at ultra-high speed frame rates (~1 MHz). Each pixel in the recorded image sequence will effectively act as an individual iNIRS detection channel. By processing signals from each channel and then combining them, we achieve similar information as in iNIRS but orders of magnitude faster than conventional iNIRS.

Thus, we can sense the rapid blood flow changes, which could be linked to neural activation. Based on our knowledge, this will be the fastest optical system for measuring cerebral blood flow in humans in vivo.

Our results will enable continuous cerebral blood flow monitoring at the bedside, helping to treat significant brain diseases and support people with disabilities.

The project will strengthen traditions of Polish development in diffusive optics. Our research will complement the development of the time-resolved diffuse optics in Poland.

The total funding of the project is 1 884 900 PLN.